.In the 1960s, US anatomist Leonard Hayflick noted that replicative tissues have a limited lot of divisions, triggered in part by telomere lessening and also eventually referred to as the Hayflick restriction. He viewed that some tissues quit portioning but refused to perish, a procedure called senescence that has actually because been implicated in several conditions as well as is currently being actually targeting by biotech and also pharmaceutical companies.The Clinical Pipeline is a column on translational and scientific research study, from seat to bedside.